By Silvio Garattini
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Extra resources for Advances in Pharmacology and Chemotherapy Volume 13
And Foltinova, P. (1971). In “Advances in Antimicrobial and Anti-neoplastic Chemotherapy” , pp. 417418. Ebringer. , and h e m e c , P. (1964). J. Protozool. 11, 153-156. Fernandes, J. , and Castellani, 0. (1958). Exp. Parasitol. 7, 224-235. Fernandes, J. , and Castellani, 0. (1959). Exp. Parasitol. 8, 480485. Fernandes, J. , and Castellani, 0. (1966). Exp. Parasitol. 18, 195-202. Fernandes, J. , and Castellani, 0. (1968). In “Mode of Action of Anti-Parasitic Drugs” (J. Rodrigues da Silva and M.
1958). Rev. Brasil. Malariol. Doencas Trop. 10, 327-330. , Tafuri, W. , and Maria, T. A. (1969). Rev. Inst. Med. Trop. Sao Paulo 11, 245-249. , and Alvarenga, N. J. (1974). Rev. Inst. Med. l’rop. Sao Paulo 16, 32-38. Browning, C. , Calver, k. , and Walls, L. P. (1946). Nature (London) 157,263-264. , and Racette, E. (1%9). Antimicrob. Ag. , p. 5-547. Camargo, E. P . (1964). Rev. Inst. Med. Trop. Sao Paulo 6, 93-100. Camargo, M. E. (1966). Rev. Inst. Med. Trop. Sao Paulo 8, 227-234. Camargo, M. , Correa, N.
1970), but must not be the only criterion used, since patients with active infection, as demonstrated by positive xenodiagnosis, may present prolonged negative serology (Marra, 1965; Rassi and Ferreira, 1971). During treatment, serological tests may be influenced by drug administration: Warmbrand et al. (1963) demonstrated that two drugs active against T . cruzi infections, primaquine and aminonucleoside of stylomycin, induced a significant decrease of antibody levels in rabbits immunized with crystalline egg albumin, probably through inhibition of nucleic acid synthesis.
Advances in Pharmacology and Chemotherapy Volume 13 by Silvio Garattini