By Frederick W. Alt (ed.), K. Frank Austen (ed.), Tasuku Honjo (ed.), Fritz Melchers (ed.), Jonathan W. Uhr (ed.), Emil R. Unanue (ed.)
Advances in Immunology, a protracted proven and hugely revered booklet, provides present advancements in addition to complete reports in immunology. Articles handle the wide variety of issues that include immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and scientific modalities. Edited and authored by way of the major scientists within the box, each one quantity presents up to date info and instructions for destiny learn.
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Extra info for Advances in Immunology, Vol. 95
Using constitutively active IKK2 to selectively engage the canonical NF-kB pathway, which is engaged by both BCR and BAFF-R signaling in mice lacking the BAFF-R, Sasaki et al. (2006) made the surprising finding that most BAFF-dependent processes, such as survival and normal B lymphocyte development, were restored by expression of IKK2. Nevertheless, this effect was found to be dependent on some level of BCR signaling. The latter conclusion was supported by the finding that these mice failed to develop or maintain an MZ compartment in the absence of the BCR positive coreceptor CD19.
281, 523–537. Gauld, S. , and Cambier, J. C. (2004). Src-family kinases in B-cell development and signaling. Oncogene 23, 8001–8006. Gauld, S. , Dal Porto, J. , and Cambier, J. C. (2002). B cell antigen receptor signaling: Roles in cell development and disease. Science 296, 1641–1642. Geier, J. , and Schlissel, M. S. (2006). Pre-BCR signals and the control of Ig gene rearrangements. Semin. Immunol. 18, 31–39. Georgopoulos, K. (2002). Haematopoietic cell-fate decisons, chromatin regulation and ikaros.
J. Immunol. 177, 2749–2754. Hardy, R. R. (2006b). B-1 B cells: Development, selection, natural autoantibody and leukemia. Curr. Opin. Immunol. 18, 547–555. Hardy, R. , and Hayakawa, K. (1995). B-lineage differentiation stages resolved by multiparameter flow cytometry. Ann. N. Y. Acad. Sci. 764, 19–24. Fate Decisions During B Lymphopoiesis 41 Hardy, R. , and Hayakawa, K. (2001). B cell development pathways. Annu. Rev. Immunol. 19, 595–621. Hardy, R. , Carmack, C. , Shinton, S. , Kemp, J. , and Hayakawa, K.
Advances in Immunology, Vol. 95 by Frederick W. Alt (ed.), K. Frank Austen (ed.), Tasuku Honjo (ed.), Fritz Melchers (ed.), Jonathan W. Uhr (ed.), Emil R. Unanue (ed.)